We’ve just been handed a miracle.
(Written by Becky)
“We’ve just been handed a miracle.” This was the title of an email Dad sent me yesterday after a chaotic exchange of phone calls back and forth between Michigan, New York and London.
Remember a few weeks ago, we mentioned that the doctors needed to test tissue matter from Mom’s biopsy for a mutation? Well, they did and we have the results. She does have this mutation. And that’s a good thing. Actually, it’s GREAT.
It’s called Epidermal Growth Factor Receptor, EFGR for short. I’ve attached a few links to some more clinical explanations, but here’s my “translation,” simple as it may be: There’s a specific genetic mutation in the tumor that is common in people in four categories: 1) never-smokers, 2) women, 3) people from Japan, and 4) people who’s cancer is an adenocarcinoma. Mom is in all categories except the third. People that are EFGR positive, like Mom, respond better to a different type of treatment. In a pill form (as opposed to chemo being delivered via an IV), this treatment targets this mutation specifically (like a sniper gun) instead of the machine-gun approach that wipes out good cells along with the bad ones. I know, I know. All you doctors out there are rolling your eyes – but bear with us “common folk.” Other advantages of this pill are the significant (and I mean very significant) reduction of the nasty side effects that are known to come along with conventional chemo.
And here’s the kicker: EGFR positive patients have shown an impressive 60% response rate which exceeds the response rate for conventional chemotherapy. If Mom were to take conventional chemotherapy, the predicted response rate for her type of cancer, and the stage that it’s in, is around 20%.
I’ve waded through tons of articles and sites and research summaries to act as a filter for you. If you are interested in this concise and clear summary with more details on EFGR, please check out this article: http://www.sciencedaily.com/releases/2005/03/050309102313.htm
I talked to Mom yesterday on the phone after she got this news and, like the rest of us, she’s so grateful for this second major ray of sunshine in this storm. (The first being the news that the cancer has not spread to her brain.) At her retreat, she met someone that did the diet she’s on and this pill for her same type of cancer and they saw results within 8 weeks. Needless to say, we are all very teary and distracted yesterday and today with this news… it has brought us a bit more HOPE.
Please, God. Heal my Mom.
His surgery for pins/screws in his foot was supposed to be this Friday, but looks like it’s pushed back a week. I’m not sure why, yet.